L-glutamic acid diethyl ester hydrochloride

L-谷氨酸二乙酯盐酸盐

What is L-glutamic acid diethyl ester hydrochloride, cas no:1118-89-4,a producer telling you the result.

CAS NO.1118-89-4

If you need the products .Please send your inquiry to us through e-mail： sales@yuansu-reagent.com

To begin with, let us tell you what is the basic information of L-glutamic acid diethyl ester hydrochloride ?

Molecular Formula	C9H18ClNO4	Molecular Weight	239.697
Density	1.08g/cm3	Boiling Point	262ºC at 760 mmHg
Flash Point	86.3ºC	Melting Point	108-110 °C(lit.)

Like many stuff, it has many synonyms as follows

EINECS 214-270-4

MFCD00012509

diethyl (2S)-2-aminopentanedioate,hydrochloride

H-Glu(OEt)-OEt.HCl

Diethyl L-Glutamate Hydrochloride

Diethyl L-glutamate hydrochloride (1:1)

H-Glu(OEt)-OEt·HCl

Diethyl glutamate hydrochloride (1:1)

L-Glutamic Acid Diethyl Ester Hydrochloride

L-Glutamic acid, diethyl ester, hydrochloride (1:1)

Glutamic acid, diethyl ester, hydrochloride (1:1)

First, the chemical is very special, some technical indexes as below

If you need the products .Please send your inquiry to us through e-mail： sales@yuansu-reagent.com

Physical property data

1. Appearance: White crystal.

2. Density (g/mL, 25 ℃): undetermined

3. Relative vapor density (g/mL, air=1): not determined

4. Melting point (º C): 108-110

5. Boiling point (º C, atmospheric pressure): undetermined

6. Boiling point (º C, 737mmHg): undetermined

7. Refractive index (C=3.6, EtOH): 22.5

8. Flash point (º C): undetermined

9. Specific rotation (º): not determined

10. Spontaneous combustion point or ignition temperature (º C): not determined

11. Vapor pressure (mmHg, 20 º C): not determined

12. Saturated vapor pressure (kPa, 60 º C): not determined

13. Combustion heat (KJ/mol): undetermined

14. Critical temperature (º C): not determined

15. Critical pressure (KPa): undetermined

16. Logarithmic value of oil-water (octanol/water) partition coefficient: undetermined

17. Explosion upper limit (%, V/V): undetermined

18. Lower explosive limit (%, V/V): not determined

19. Solubility: undetermined

toxicology data

1. Acute toxicity: intraperitoneal LD50 in mice:> 2gm/kg

Ecological data

None

Molecular structure data

1. Molar refractive index: unavailable

2. Molar volume (cm3/mol): No available

3. Waiting for Zhang Bi Rong (90.2K): No available

4. Surface tension (dyne/cm): No available

5. Dielectric constant: No available

6. Polarization rate (10-24cm3): No available

7. Single isotope mass: 239.092436 Da

8. Nominal mass: 239 Da

9. Average quality: 239.6965 Da

Calculate chemical data

1. Reference value for hydrophobic parameter calculation (XlogP): None

2. Number of hydrogen bond donors: 2

3. Number of hydrogen bond acceptors: 5

4. Number of rotatable chemical bonds: 8

5. Number of tautomers: None

6. Topological molecule polarity surface area 78.6

7. Number of heavy atoms: 15

8. Surface charge: 0

9. Complexity: 193

10. Number of isotopic atoms: 0

11. Determine the number of atomic stereocenters: 1

12. Uncertain number of atomic stereocenters: 0

13. Determine the number of chemical bond stereocenters: 0

14. Number of uncertain chemical bond stereocenters: 0

15. Number of covalent bond units: 2

Nature and stability

Stable at room temperature and pressure, avoiding contact with strong oxides

Storage

-Sealed storage at 20 ° C

Second, the Synthetic Route we will recommend is the most important for your reference?

First, synthesis line ofL-glutamic acid diethyl ester hydrochloride CAS NO.1118-89-4 as follows

synthetic method

Third, what is the usage of L-glutamic acid diethyl ester hydrochloride CAS NO.1118-89-4 ? pleas see below

If you need the products .Please send your inquiry to us through e-mail：sales@yuansu-reagent.com

Usage: Under acidic conditions, L-glutamic acid diethyl ester hydrochloride dissociates into positive and negative ions. The positive ion part is diethyl glutamate, and the negative ion part is hydrochloride ion.

It can serve as an acidic catalyst and participate in esterification, acylation and other reactions

Main usages:

Used for the synthesis of 5,10-methylene-5,6,7,8-tetrahydro-8,10-dideazaminopterin, Cas no. 103003-96-9

Used for the synthesis of diethyl (2S)-2-isocyanatopentanedioate Cas no. 145080-95-1

Used for the synthesis of diethyl (2S)-2-pyrrol-1-ylpentanedioate Cas no. 157034-04-3

Besides Safety Information of L-glutamic acid diethyl ester hydrochloride CAS NO.1118-89-4 is also important when handling it

Hazard Codes	Xi
WGK Germany	3
H．S．Code：	2922 4999.90
TSCA	Yes
HazardClass	IRRITANT

What is the appearance ofL-glutamic acid diethyl ester hydrochloride CAS NO.1118-89-4? Please see the picture ofL-glutamic acid diethyl ester hydrochloride CAS NO.1118-89-4, below

If you need the products .Please send your inquiry to us through e-mail： sales@yuansu-reagent.com

Specification of L-glutamic acid diethyl ester hydrochloride CAS NO.1118-89-4, is below

Apperance: white crystalline powder

Assay: 99 min by HPLC

IR identity: conform

IR picture of L-glutamic acid diethyl ester hydrochloride CAS NO.1118-89-4 is as follows,

H-NMR Spectrum picture of L-glutamic acid diethyl ester hydrochloride CAS NO.1118-89-4 is as follows,

Reference of Article cited for your reference below,

(1)

Synthesis of N,N′-diacyl bis-glutamic acid derivatives and their influence on the receptor binding of3H-L-glutamate

Publication Date: 1988

Publication Name: Pharmaceutical Chemistry Journal

(2)

Unilateral blockade of excitatory amino acid receptors in the nucleus tractus solitarii produces an inhibiton of baroreflexes in rats

Publication Date: 1991

Publication Name: Naunyn-Schmiedeberg's Archives of Pharmacology

(3)

New Approaches to the Enzymatic Production of Oligopeptides: Synthesis of the “Delicious Peptide” and its Fragments

Publication Date: 1994

Publication Name: Advances in Bioprocess Engineering