2-Amino-4-Methoxy-5-(3-Morpholinopropoxy)benzonitrile

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What is 2-Amino-4-Methoxy-5-(3-Morpholinopropoxy)benzonitrile, cas no:675126-27-9,a producer telling you the result.

                                                          CAS NO.675126-27-9

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To begin with, let us tell you what is the basic information of 2-Amino-4-Methoxy-5-(3-Morpholinopropoxy)benzonitrile ?

Molecular Formula

C15H21N3O3

Molecular Weight

291.345

Density

1.2±0.1 g/cm3

Boiling Point

498.0±45.0 °C at 760 mmHg

Flash Point

255.0±28.7 °C

Exact Mass

291.158295

 

Like many stuff, it has many synonyms as follows

2-amino-4-methoxy-5-(3-morpholin-4-ylpropoxy)benzonitrile

2-Amino-4-methoxy-5-[3-(4-morpholinyl)propoxy]benzonitrile

Benzonitrile, 2-amino-4-methoxy-5-[3-(4-morpholinyl)propoxy]-

 

First, the chemical is very special, some technical indexes as below

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Second, the Synthetic Route we will recommend is the most important for your reference?

 

First, synthesis line of 2-Amino-4-Methoxy-5-(3-Morpholinopropoxy)benzonitrile CAS NO.675126-27-9  as follows

The main method of manufacture

 

Third, what is the usage of  2-Amino-4-Methoxy-5-(3-Morpholinopropoxy)benzonitrile  CAS NO.675126-27-9  pleas see below

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Usage:

Used for pharmaceutical industry

Other usage:

Used for the synthesis of Gefitinib, Cas no. 184475-35-2

Used for the synthesis of O-Desmethyl gefitinib Cas no. 847949-49-9

Used for the synthesis of Gefitinib impurity 2 Cas no. 246512-44-7

 

 

Besides Safety Information of 2-Amino-4-Methoxy-5-(3-Morpholinopropoxy)benzonitrile  CAS NO.675126-27-9  is also important when handling it

 

 

Hazard Codes 

Xi

WGK Germany 

3

HSCode

2933 5990.99

TSCA 

Yes

HazardClass 

IRRITANT

 

 

What is the appearance of 2-Amino-4-Methoxy-5-(3-Morpholinopropoxy)benzonitrile  CAS NO.675126-27-9?   Please see the picture of 2-Amino-4-Methoxy-5-(3-Morpholinopropoxy)benzonitrile  CAS NO.675126-27-9, below

 

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Specification of 2-Amino-4-Methoxy-5-(3-Morpholinopropoxy)benzonitrile  CAS NO.675126-27-9, is below

Apperance: yellow to brown crystal solid

Assay: 98 min by GC

IR identity: conform

 

Reference of  Article cited for your reference below,

(1)

Method for preparing 4-(3-chloro-4-fluoroaniline)-6-acetoxy-7-methoxy quinazoline hydrochloride

Publication Number: WO-2021212536-A1

Priority Date: 2020-04-25

(2)

Process for the preparation of 4-(3′-chloro-4′-fluoroanilino) -7-methoxy-6-(3-morpholinopropoxy) quinazoline

US-7705145-B2; Grant Date: 2010-04-27

(3)

Process for the preparation of 4-(3′-chloro-4′-fluoroanilino) -7-methoxy-6-(3-morpholinopropoxy) quinazoline

US-7705145-B2; Grant Date: 2010-04-27