1-(2-Hydroxyethyl)-4-methylpiperazine
What is 1-(2-Hydroxyethyl)-4-methylpiperazine, cas no:5464-12-0,a producer telling you the result.
CAS NO.5464-12-0
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To begin with, let us tell you what is the basic information of 1-(2-Hydroxyethyl)-4-methylpiperazine ?
Molecular Formula |
C7H16N2O |
Molecular Weight |
144.215 |
Density |
1.0±0.1 g/cm3 |
Boiling Point |
234.9±20.0 °C at 760 mmHg |
Flash Point |
106.1±20.4 °C |
Melting Point |
39-41°C |
Like many stuff, it has many synonyms as follows
MFCD03840691 |
1-Piperazineethanol, 4-methyl- |
2-(4-methylpiperazin-1-yl)ethanol |
2-(4-Methyl-1-piperazinyl)ethanol |
1-(N-hydroxyethyl)-4-methyl piperazine |
First, the chemical is very special, some technical indexes as below
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Molecular structure data
1. Molar refractive index: 41.14
2. Molar volume (cm3/mol): 143.6
3. Waiting ratio (90.2K): 350.4
4. Surface tension (dyne/cm): 35.4
5. Polarization rate (10-24cm3): 16.31
Calculate chemical data
1. Reference value for hydrophobic parameter calculation (XlogP): -0.6
2. Number of hydrogen bond donors: 1
3. Number of hydrogen bond acceptors: 3
4. Number of rotatable chemical bonds: 2
5. Number of tautomers: None
6. Topological molecular polarity surface area 26.7
7. Number of heavy atoms: 10
8. Surface charge: 0
9. Complexity: 89.6
10. Number of isotopic atoms: 0
11. Determine the number of atomic stereocenters: 0
12. Uncertain number of atomic stereocenters: 0
13. Determine the number of chemical bond stereocenters: 0
14. Number of uncertain chemical bond stereocenters: 0
15. Number of covalent bond units: 1
Second, the Synthetic Route we will recommend is the most important for your reference?
First, synthesis line of 1-(2-Hydroxyethyl)-4-methylpiperazine CAS NO.5464-12-0 as follows
The main method of manufacture
- (2-hydroxyethyl) -4-methylpiperazine can be synthesized by various methods, among which the commonly used method is to react 4-methylpiperazine with ethoxyvinyl ammonium chloride to obtain
Third, what is the usage of 1-(2-Hydroxyethyl)-4-methylpiperazine CAS NO.5464-12-0 ? pleas see below
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Usage:
1- (2-hydroxyethyl) -4-methylpiperazine is widely used in the pharmaceutical industry.
Other usage:
Used for the synthesis of 3-methoxy-4-[2-(4-methylpiperazin-1-yl)ethoxy]benzaldehyde, Cas no. 646071-39-8
Used for the synthesis of 4-[2-(4-Methyl-1-piperazinyl)ethoxy]aniline Cas no. 38948-28-6
Used for the synthesis of 2-(4-methylpiperazin-1-yl)ethyl 1-cyclohexylcyclohexane-1-carboxylate Cas no. 3563-46-0
Besides Safety Information of 1-(2-Hydroxyethyl)-4-methylpiperazine CAS NO.5464-12-0 is also important when handling it
Hazard Codes |
Xi |
WGK Germany |
3 |
H.S.Code: |
2933599090 |
TSCA |
Yes |
HazardClass |
IRRITANT |
What is the appearance of 1-(2-Hydroxyethyl)-4-methylpiperazine CAS NO.5464-12-0? Please see the picture of 1-(2-Hydroxyethyl)-4-methylpiperazine CAS NO.5464-12-0, below
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Specification of 1-(2-Hydroxyethyl)-4-methylpiperazine CAS NO.5464-12-0, is below
Apperance: colorless to light yellow liquid.
Assay: 99 min by GC
IR identity: conform
Water:0.5% max by K.F.
C-HMR picture of 1-(2-Hydroxyethyl)-4-methylpiperazine CAS NO.5464-12-0 is as follows,
Reference of Article cited for your reference below,
(1)
Publication Name: European Food Research and Technology
Publication Date: 2015-01-18
DOI: 10.1007/s00217-015-2413-2
(2)
Publication Date: 2015
Publication Name: European Food Research and Technology
(3)
Structure-Guided Discovery of Selective Mcl-1 Inhibitors
Publication Date: 2019
Publication Name: Synfacts