4-Hydroxypiperidine

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What is 4-Hydroxypiperidine, cas no:5382-16-1,a producer telling you the result.

CAS NO.5382-16-1

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To begin with, let us tell you what is the basic information of 4-Hydroxypiperidine ?

Molecular Formula	C5H11NO	Molecular Weight	101.147
Density	1.0±0.1 g/cm3	Boiling Point	222.0±0.0 °C at 760 mmHg
Flash Point	107.8±0.0 °C	Melting Point	86-90 °C

Like many stuff, it has many synonyms as follows

EINECS 226-373-1

MFCD00005999

4-Piperidinol

4PPOL

4-Hydroxypiperidine

4-Hydropiperidine

piperdin-4-ol

AURORA KA-1006

4-piperidinyl

4-hydroxy-piperidine

Piperidin-4-ol

4-oxypiperidine

First, the chemical is very special, some technical indexes as below

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Physical property data

1. Characteristic: undetermined

2. Density (g/mL, 25/4 ℃): not determined

3. Relative vapor density (g/mL, air=1): not determined

4. Melting point (º C): 86-90

5. Boiling point (º C, atmospheric pressure): 108-114

6. Boiling point (º C, 5.2kPa): undetermined

7. Refractive index: undetermined

8. Flash point (℃): 107

9. Specific rotation (º): not determined

10. Spontaneous combustion point or ignition temperature (º C): not determined

11. Vapor pressure (kPa, 25 º C): not determined

12. Saturated vapor pressure (kPa, 60 º C): not determined

13. Combustion heat (KJ/mol): undetermined

14. Critical temperature (º C): not determined

15. Critical pressure (KPa): undetermined

16. Logarithmic value of oil-water (octanol/water) partition coefficient: undetermined

17. Explosion upper limit (%, V/V): undetermined

18. Lower explosive limit (%, V/V): not determined

19. Solubility: soluble in water

toxicology data

Currently unavailable

Ecological data

Usually not harmful to water, do not discharge materials into the surrounding environment without government permission

Molecular structure data

Molecular property data:

1. Molar refractive index: 27.99

2. Molar volume (m3/mol): 99.4

3. Waiting for Zhang Biarong (90.2K): 239.7

4. Surface tension (dyne/cm): 33.7

5. Polarization rate (10-24cm3): 11.09

Calculate chemical data

1. Reference value for hydrophobic parameter calculation (XlogP): -0.3

2. Number of hydrogen bond donors: 2

3. Number of hydrogen bond acceptors: 2

4. Number of rotatable chemical bonds: 0

5. Number of tautomers: None

6. Topological molecule polarity surface area 32.3

7. Number of heavy atoms: 7

8. Surface charge: 0

9. Complexity: 50

10. Number of isotopic atoms: 0

11. Determine the number of atomic stereocenters: 0

12. Uncertain number of atomic stereocenters: 0

13. Determine the number of chemical bond stereocenters: 0

14. Number of uncertain chemical bond stereocenters: 0

15. Number of covalent bond units: 1

Nature and stability

Stable under normal temperature and pressure

Storage method

Avoid light, store in a cool and dry place, and seal tightly

Second, the Synthetic Route we will recommend is the most important for your reference?

First, synthesis line of 4-Hydroxypiperidine CAS NO.5382-16-1 as follows

Manufacturing method:

There are various methods for preparing 4-hydroxypyridine, including:By reacting piperidine with sodium hypochlorite or potassium hypochlorite, 4-chloropyridine is obtained. Then, 4-chloropyridine is converted to 4-hydroxypyridine through the reaction of cuprous chloride and sodium hydroxide.-4-hydroxypyridine is obtained by reacting sodium hydroxide with 4-piperidone.

Third, what is the usage of 4-Hydroxypiperidine CAS NO.5382-16-1 ? pleas see below

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Non ionic surfactant: 4-hydroxypyridine can be used as a non-ionic surfactant in some paint, leather, and textile industries.

Other usage:

Used for the synthesis of 1-(5-chloropyrimidin-2-yl)piperidin-4-ol, Cas no. 1108164-37-9

Used for the synthesis of 3-piperidin-4-yloxypyridine Cas no. 310881-48-2

Used for the synthesis of (4-hydroxypiperidin-1-yl)-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]methanone Cas no. 1100094-82-3

Besides Safety Information of 4-Hydroxypiperidine CAS NO.5382-16-1 is also important when handling it

Hazard Codes	Xi
WGK Germany	3
H．S．Code：	29333220.00
TSCA	Yes
HazardClass	IRRITANT

What is the appearance of 4-Hydroxypiperidine CAS NO.5382-16-1? Please see the picture of 4-Hydroxypiperidine CAS NO.5382-16-1, below