3-Methylaminopiperidine dihydrochloride

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What is 3-Methylaminopiperidine dihydrochloride, cas no. 127294-77-3,a producer telling you the result.

                                                                CAS NO. 127294-77-3

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To begin with, let us tell you what is the basic information of 3-Methylaminopiperidine dihydrochloride ?

Molecular Formula

C6H16Cl2N2

Molecular Weight

187.111

Melting Point

199-200°C

Boiling Point

253.7ºC at 760 mmHg

Flash Point

107.2ºC

Exact Mass

186.069061

 

Like many stuff, it has many synonyms as follows

MFCD00673143

3-Piperidinamine, N-methyl-, hydrochloride (1:2)

3-Methylamino-piperidine dihydrochloride

N-methylpiperidin-3-amine,dihydrochloride

3-(Methylamino)piperidine dihydrochloride

N-Methylpiperidin-3-amindihydrochlorid

First, the chemical is very special, some technical indexes as below

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Physical property data

1. Appearance: White solid

2. Density (g/mL, 20 ): undetermined

3. Relative vapor density (g/mL, air=1): not determined

4. Melting point (º C): 199-200

5. Boiling point (º C, atmospheric pressure): undetermined

6. Boiling point (º C, KPa): undetermined

7. Refractive index: undetermined

8. Flash point (º C): undetermined

9. Specific rotation (º): not determined

10. Spontaneous combustion point or ignition temperature (º C): not determined

11. Vapor pressure (Pa, 20 º C): not determined

12. Saturated vapor pressure (KPa, 20 º C): not determined

13. Combustion heat (KJ/mol): undetermined

14. Critical temperature (º C): not determined

15. Critical pressure (KPa): undetermined

16. Logarithmic value of oil-water (octanol/water) partition coefficient: undetermined

17. Explosion upper limit (%, V/V): undetermined

18. Lower explosive limit (%, V/V): not determined

19. Solubility: undetermined

toxicology data

Currently unavailable

Ecological data

Currently unavailable

Molecular structure data

1. Molar refractive index: unavailable

2. Molar volume (cm3/mol): No available

3. Waiting for Zhang Bi Rong (90.2K): No available

4. Surface tension (dyne/cm): No available

5. Dielectric constant: No available

6. Polarization rate (10-24cm3): No available

7. Single isotope mass: 186.069054 Da

8. Nominal mass: 186 Da

9. Average quality: 187.1106 Da

Calculate chemical data

1. Reference value for hydrophobic parameter calculation (XlogP): None

2. Number of hydrogen bond donors: 4

3. Number of hydrogen bond acceptors: 2

4. Number of rotatable chemical bonds: 1

5. Number of tautomers: None

6. Topological molecular polarity surface area 24.1

7. Number of heavy atoms: 10

8. Surface charge: 0

9. Complexity: 63.5

10. Number of isotopic atoms: 0

11. Determine the number of atomic stereocenters: 0

12. Uncertain number of atomic stereocenters: 1

13. Determine the number of chemical bond stereocenters: 0

14. Number of uncertain chemical bond stereocenters: 0

15. Number of covalent bond units: 3

 

Second, the Synthetic Route we will recommend is the most important for your reference?

First, synthesis line of 3-Methylaminopiperidine dihydrochloride CAS NO. 127294-77-3  as follows

Manufacturing method:

A common method for preparing 3-methylaminopiperidine hydrochloride is to react pyridine with methylamine in the presence of hydrochloric acid. The specific synthesis method may vary, and an appropriate synthesis scheme should be selected based on different experimental conditions and requirements.

 

Third, what is the usage of  3-Methylaminopiperidine dihydrochloride  CAS NO. 127294-77-3  pleas see below

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Usage:

Organic synthesis: It can be used as a catalyst or additive to participate in organic reactions such as carbonylation and cyclization reactions.

 

Besides Safety Information of 3-Methylaminopiperidine dihydrochloride  CAS NO.127294-77-3  is also important when handling it

 

Hazard Codes 

Xi

WGK Germany 

3

HSCode

2933 3990.99

TSCA 

Yes

HazardClass 

IRRITANT

 

 

What is the appearance of 3-Methylaminopiperidine dihydrochloride  CAS NO.127294-77-3?   Please see the picture of 3-Methylaminopiperidine dihydrochloride  CAS NO.127294-77-3, below

 

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Specification of 3-Methylaminopiperidine dihydrochloride  CAS NO.127294-77-3, is below

Apperance: white crystal solid

Assay: 99 min by HPLC

IR identity: conform

Water:0.5% max by K.F.

 

Reference of  Article cited for your reference below,

(1)

Method for producing quinolone carboxylic acid derivative

Publication Number: CA-2679852-C

Priority Date: 2007-03-30

Grant Date: 2013-08-06

(2)

METHOD FOR THE PRODUCTION OF QUINOLONA CARBOXYLIC ACID DERIVATIVE

Publication Number: BR-PI0809220-A2

Priority Date: 2007-03-30

(3)

Method for producing quinolone carboxylic acid derivative

Publication Number: EP-2130827-A1

Priority Date: 2007-03-30