6-Hydroxy-7-methoxy-3,4-dihydroquinazolin-4-one
What is 6-Hydroxy-7-methoxy-3,4-dihydroquinazolin-4-one, cas no. 179688-52-9,a producer telling you the result.
CAS NO. 179688-52-9
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To begin with, let us tell you what is the basic information of 6-Hydroxy-7-methoxy-3,4-dihydroquinazolin-4-one CAS NO. 179688-52-9 ?
Molecular Formula |
C9H8N2O3 |
Molecular Weight |
192.171 |
Density |
1.5±0.1 g/cm3 |
Boiling Point |
503.3±40.0 °C at 760 mmHg |
Flash Point |
258.2±27.3 °C |
Melting Point |
291 °C |
Like many stuff, it has many synonyms as follows
MFCD07787563 |
6-Hydroxy-7-methoxy-3,4-dihydroquinazolin-4-one |
6-hydroxy-7-(methyloxy)-4(3H)-quinazolinone |
6-Hydroxy-7-methoxy-4(3H)-Quinazolinone |
6-Hydroxy-7-methoxychinazolin-4(3H)-on |
6-Hydroxy-7-methoxyquinazolin-4(3H)-one |
6-hydroxy-7-methoxyquinazoline-4(3H)-one |
6-Hydroxy-7-methoxy-4(1H)-quinazolinone |
4(3H)-Quinazolinone, 6-hydroxy-7-methoxy- |
3,4-dihydro-4-oxo-6-hydroxy-7-methoxy-quinazoline |
6-Hydroxy-7-methoxy-3H-Quinazolin-4-one |
First, the chemical is very special, some technical indexes as below
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Second, the Synthetic Route we will recommend is the most important for your reference?
First, synthesis line of 6-Hydroxy-7-methoxy-3,4-dihydroquinazolin-4-one CAS NO. 179688-52-9 as follows
Main method of manufacture:Introducing methoxy and hydroxyl functional groups onto quinazolin-4-one to synthesize 6-hydroxy-7-methoxyquinazolin-4-one
Third, what is the usage of 6-Hydroxy-7-methoxy-3,4-dihydroquinazolin-4-one CAS NO. 179688-52-9 ? pleas see below
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The uses of 179688-52-9 include as an intermediate for gefitinib.
179688-52-9, chemical name 6-hydroxy-7-methoxy-3H-quinazolin-4-one, is an organic compound with the molecular formula C9H8N2O3 and a molecular weight of 192.1714. This compound is considered an intermediate of gefitinib, a drug used to treat certain types of cancer. In addition, the compound has been mentioned as one of the downstream products of 6-hydroxy-7-methoxyquinazolin-4-one, further confirming its potential application in drug synthesis.
In summary, 179688-52-9 plays a crucial role as an important organic intermediate in the field of drug synthesis, particularly in the synthesis of gefitinib.
Other usages as below
Used for the synthesis of Gefitinib Cas no. 184475-35-2
Used for the synthesis of 4-(3-chloro-2-fluoroanilino)-6-hydroxy-1H-quinazolin-7-one
Cas no. 848440-15-3
Used for the synthesis of 6-Acetoxy-4-chloro-7-methoxyquinazoline
,Cas no. 230955-75-6
Besides Safety Information of 6-Hydroxy-7-methoxy-3,4-dihydroquinazolin-4-one CAS NO.179688-52-9 is also important when handling it
Hazard Codes |
Xi |
WGK Germany |
3 |
H.S.Code: |
2933990099 |
TSCA |
Yes |
HazardClass |
IRRITANT |
What is the appearance of 6-Hydroxy-7-methoxy-3,4-dihydroquinazolin-4-one CAS NO.179688-52-9? Please see the picture of 6-Hydroxy-7-methoxy-3,4-dihydroquinazolin-4-one CAS NO.179688-52-9, below
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Specification of 6-Hydroxy-7-methoxy-3,4-dihydroquinazolin-4-one CAS NO.179688-52-9, is below
Apperance: white to light yellow crystal powder
Assay: 98 min by HPLC
IR identity: conform
Water:0.5% max by K.F.
Reference of Article cited for your reference below,
Reference of Article cited for your reference below,
(1)
- An activating mutant quinazoline inhibitor of epidermal growth factor receptor
JP-5894714-B1; Grant Date: 2016-03-30
(2)
- An activating mutant quinazoline inhibitor of epidermal growth factor receptor
JP-5894714-B1; Grant Date: 2016-03-30