5-Chlorothiophene-2-carboxylic Acid
What is 5-Chlorothiophene-2-carbonyl chloride, cas no. 42518-98-9,a producer telling you the result.
CAS NO. 42518-98-9
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To begin with, let us tell you what is the basic information of 5-Chlorothiophene-2-carbonyl chloride CAS NO. 42518-98-9 ?
Molecular Weight |
181.040 |
Flash Point |
89.2±21.8 °C |
Molecular Formula |
C5H2Cl2OS |
Boiling Point |
223.9±20.0 °C at 760 mmHg |
Density |
1.5±0.1 g/cm3 |
Melting Point |
4 °C |
Like many stuff, it has many synonyms as follows
Rivaroxaban Impurity 82 |
5-Chloro-thiophene-2-carbonyl chloride |
5-Chloro-2-thiophenecarbonyl chloride |
2-Thiophenecarbonyl chloride, 5-chloro- |
5-chlorothiophene-2-carbonyl chloride |
5-Chloro-2-thenoyl Chloride |
5-Chorothiophene-2-Carbonyl Chloride |
First, the chemical is very special, some technical indexes as below
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Security information:
5-Chloro-2-acylchlorothiophene belongs to organic chlorinated compounds and has certain toxicity.
When handling and storing this compound, appropriate protective gloves, glasses, and protective clothing should be worn.
Avoid contact with skin, eyes, and respiratory tract to avoid irritation or damage.
During use, good ventilation should be maintained and contact with combustible materials should be avoided.
When handling waste, relevant safety operating procedures and regulations should be followed.
Second, the Synthetic Route we will recommend is the most important for your reference?
First, synthesis line of 5-Chlorothiophene-2-carbonyl chloride CAS NO. 42518-98-9 as follows
5-Chloro-2-acylchlorothiophene can be obtained by reacting 5-chloro-2-ketothiophene with thionyl chloride.
The reaction conditions are generally carried out in an inert atmosphere at lower temperatures.
Third, what is the usage of 5-Chlorothiophene-2-carbonyl chloride CAS NO. 42518-98-9 ? pleas see below
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5-Chloro-2-acylchlorothiophene is commonly used as a reagent in organic synthesis.
In the agricultural field, it is often used as an intermediate for insect insecticides.
Other usages as below
Used for the synthesis of 2-(5-chlorothiophen-2-yl)acetic acid Cas no. 13669-19-7
Used for the synthesis of 1-(5-chlorothiophen-2-yl)propan-1-one Cas no. 32427-82-0
Used for the synthesis of 2-[(5-chlorothiophene-2-carbonyl)amino]-2-methylpropanoic acid ,Cas no. 869548-36-7
Besides Safety Information of 5-Chlorothiophene-2-carbonyl chloride CAS NO. 42518-98-9 is also important when handling it
Hazard Codes |
Xi |
WGK Germany |
3 |
H.S.Code: |
2934999090 |
TSCA |
Yes |
HazardClass |
IRRITANT |
What is the appearance of 5-Chlorothiophene-2-carbonyl chloride CAS NO. 42518-98-9? Please see the picture of 5-Chlorothiophene-2-carbonyl chloride CAS NO. 42518-98-9, below
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Specification of 5-Chlorothiophene-2-carbonyl chloride CAS NO. 42518-98-9, is below
Apperance: white to off-white crystal powder
Density: 1.543~1.544g/cm ³
Flash point: 89.2 ℃
Melting point: 151~155 ℃
Vapour pressure: 0.0937mmHg at 25 ℃
IR identity: conform
Water:0.5% max by K.F.
HNMR picture of 5-Chlorothiophene-2-carbonyl chloride CAS NO. 42518-98-9 is as follows,
Reference of Article cited for your reference below,
(1)
Publication Name: Chromatographia
Publication Date: 2016-02-08
DOI: 10.1007/s10337-016-3038-8
(2)
Synthesis of Substituted Alkoxythiophenes: Thiophene Analogues of Dazoxiben
Publication Name: Monatshefte für Chemie / Chemical Monthly
Publication Date: 1999-05-01
DOI: 10.1007/pl00010245
(3)
Publication Date: 2016
Publication Name: Chromatographia