Caronic anhydride
What is 6,6-Dimethyl-3-oxabicyclo[3.1.0]hexane-2,4-dione, cas no. 67911-21-1,a producer telling you the result.
CAS NO. 67911-21-1
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To begin with, let us tell you what is the basic information of Caronic anhydride CAS NO. 67911-21-1 ?
Molecular Weight |
140.137 |
Flash Point |
112.7±15.9 °C |
Density |
1.3±0.1 g/cm3 |
Boiling Point |
246.3±9.0 °C at 760 mmHg |
Molecular Formula |
C7H8O3 |
Melting Point |
52-55ºC |
Like many stuff, it has many synonyms as follows
6,6-Dimethyl-3-oxabicyclo[3.1.0]hexane-2,4-dione
Caronic anhydride
3-oxabicyclo[3.1.0]hexane-2,4-dione, 6,6-dimethyl-
First, the chemical is very special, some technical indexes as below
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Second, the Synthetic Route we will recommend is the most important for your reference?
First, synthesis line of Caronic anhydride CAS NO. 67911-21-1 as follows
There are two routes for the synthesis of carbolic anhydride, and the first generation route requires 12 linear synthesis steps, which is costly.
The second generation route consists of three stages of synthesis, which involve benzylamine amination, reduction, and removal of benzyl groups to obtain carmonic anhydride.
Enzymatic catalysis is an application method in the synthesis of carmonic anhydride, which involves treating amines with oxidase and then treating them with sodium bisulfite to obtain the target compound
Synthesis lines in details as below
Third, what is the usage of Caronic anhydride CAS NO. 67911-21-1 ? pleas see below
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Caronic anhydride is an important compound with extensive application value.
Boprevir is a type of hepatitis C treatment drug, also known as Victrelis. Its molecular structure contains fragment P2.
Pfizer's COVID-19 oral drug Paxlovid also contains fragment P2, so the demand for carborunic anhydride also increases.
Mainly used for Intermediate of dabigatran ester
Other usages as below
Used for the synthesis of 3,3-Dimethylcyclopropane-1,2-dicarboximide
Cas no. 194421-56-2
Used for the synthesis of 6,6-dimethyl-3-azabicyclo[3.1.0]hexane,hydrochloride
Cas no. 943516-55-0
Used for the synthesis of
6,6-Dimethyl-3-azabicyclo[3.1.0]hexane
,Cas no. 943516-54-9
Besides Safety Information of Caronic anhydride CAS NO. 67911-21-1 is also important when handling it
Hazard Codes |
Xi |
WGK Germany |
3 |
H.S.Code: |
2917209090 |
TSCA |
Yes |
HazardClass |
IRRITANT |
What is the appearance of Caronic anhydride CAS NO. 67911-21-1? Please see the picture of Caronic anhydride CAS NO. 67911-21-1, below
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Specification of Caronic anhydride CAS NO. 67911-21-1, is below
Apperance: white to off-white crystal powder
Assay: 98 %~103% by GC
IR identity: conform
Water:0.5% max by K.F.
Melting point:52~55℃
HNMR picture of Caronic anhydride CAS NO. 67911-21-1 is as follows,
Reference of Article cited for your reference below,
(1)
Modulators of G-protein coupled receptors
Publication Number: KR-20210008834-A
Priority Date: 2018-03-23
(2)
EP-1633711-B1; Grant Date: 2010-11-24
(3)
JP-6986789-B2; Grant Date: 2021-12-22